Alcetam
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Piracetam
It is nootropic agent, that is a psychotropic drug which improves the functioning of the brain involved in cognitive processes e.g. memory, thorough learn¬ing in normal and in subnormal conditions. The beneficial effects are due to improved microcirculation, promotes the metabolism and modulates neurotransmission. Protect cerebral cor¬tex against hypoxia.
INDICATIONS: Mental retardation, Learning problems in children, behavioural problem and confusion state in elderly patients, cerebro-vascular accidents, cerebral insufficiencies.
CONTRAINDICATIONS : Severe renal and hepatic impairment. Hypersensitivity.
SAFETY PROFILE : Drug should be with¬drawn gradually, Patients with history of renal & hepatic diseases cardiac disorders.
ADVERSE EFFECTS: Insomnia, nervousness, increased motor activity, depression, weight gain, diarrhoea, skin rashes, epigastric distress, CNS stimulation. GI obstruction or perforation epilepsy, phaeochromocytoma, extra pyramidal symptoms.
DRUG INTERACTIONS : Warfarin and thyroid hormones, inhibits and severe sickling of RBC's. oral anticoagulants : Increased prothrombin time.
DOSAGE : Adults : 800mg t.i.d. Children 50mg/kg body weight in 3 separate doses. Reduce the initial dose by half after obtaining desired result.