altaxel
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PACLITAXEL:It is a diterpenoid compound with anti-tumor activity. It binds specifically to the B tubulin subunit of microtubule and appears to antagonize the disassembly of this cytoskeleton protein.
Indications:Metastasis ovarian and breast cancer.
Dosage:175mg per square meter by IV infusion over 3rs. Repeat every 3 weeks. Preterit with corticosteroids, antihistaminics and H2 antagonists
Contra-indications:Hypersensitivity.
Special Precautions:Monitor hematological functions.
Pediatrics: Not recommended.
Pregnancy: Not usually prescribed.
Lactation: Not advised.
Side effect: Bone marrow depression, hypersensitivity reactions, malign. Chest pain bradycardia, a stocking-glove sensory neuropathy mycoses, nausea, vomiting, diarrhea, alopecia.