bal dimercaporl
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DIMERCAPROL: It binds to metals which produce toxicity by interacting with sulfhydryl containing dnzymes in the body. The dimercaprol-metal complex spontaneously dissorciates at a slow rate:als dimercaprol is partly oxidise in the body; further emphasinzing the necessity ot have excess dimercaprol available in the But large amounts should not be given at a time.
Indications : Postisoning due to aresnic, mercury gold, bismuth, nickel, thalium antimony. As an adjuvant ot cal disod, edetate n lead poisoning and in wilson’s disease.
Dosage : Usually 100mg every 4hrs, for 48 hrs then 100mg 8hrly for 8-10 days. Wilson’s disease 300mg daily for 10 days every 2nd month for long periods.
Contra Indications: Iron & Lead oisoning.
Special Precautions : Hypertension, hepatic damage. Antihistamincs given 1/2 hrs. before reduces intensity of adverse effects.
Side effects: Rise in BP, tachycardia, vomiting tinging and burining sesation infammation of mucous membranes, sweating, carmps, headache & anxiety.
Drug Interactions: None reported