bleotex
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BLEOMYCIN: This is a mixture of closely related antitumour antibiotics. It chelates copper or iron, intercalates between DNA strnds causes chain scission and inhibits repair
Indications: Testicular tumour, squamous cell carcinoma of skin, head & neck, genitourinary tract & oesophagus, Hodgkin's lymphoma. Malignancy o lungs & cervix. Dosage: 30 mg twice weekly in average cases.
Dosages: 30 mg twice weekly in average cases, otherwise dose can be varied between 15 mg daily to 15 mg weekly. Total dose: 300-400 mg.
Contra-indications: Dot mix glutathione with bleomycin. Pre-existing lung diseases. Special Precautions: Pediatrics: Safety not established. Pregnancy: Should not be used. Lactation: Should not be used. Elderly: Dose adjustment is necessary. Side-effects: Mucocutaneous toxicity, pulmonary fibrosis, Dermatitis. Nephrotoxicity.Hepatic toxicity.