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Flutamide

flutamide is a hormonal therapy. It is given in the treatment of prostate cancer. There are several types of hormonal therapies. The most suitable one is administered by the doctor. Hormonal therapies interfere with a type of hormones in a human body. Hormones are produced naturally in a human. The hormones work as messengers and help to control the activities in a body.

Most of the prostate cancers require supplies of the male hormone testosterone to grow. Flutamide has a structure which is identical with testosterone. flutamide functions by preventing testosterone from attaching itself to the receptors on the prostate cancer cells. Consequently, the cancer cells in a body grow more slowly or stop growing without testosterone

Technical detail:

Indications:Advanced prostates cancer.

Dosage: 250 mg three times daily.

Contra indications:History of thrombo-emblic disorders, severe chronic depression.

Special Precautions: Monitor liver function tests periodically, Fluid
retention can occur i patients with cardiac disease.
Pediatrics: Not recommended.
Pregnancy: safety not established.
Lection : Safety not established.
Elderly: No special problem

Side effects: Nausea, vomiting diarrhea, stomatis, shedding of mucosa, Gynaecomastia, breast tenderness, glactorrhoea, insomnia, C.N.S disturbances.

Drug interactions:Wafarin increase prothrombin time.

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