leukeran
Changing product quantity in your shopping cart
When you have selected your item you can see your shopping cart items, quantity and total. You can change the quantity by entering the number of quantity you want. Then press 'Update' to change the quantity required.
|
Leukeran (other)
US Brand: Leukeran
Manufacturer: Other
|
|
CHIORORAMBUCIL is a very slow acng alkylating agent, especially active on lymphoid tissue; myeloid tissue is largelyspared. it is the drug of choice for long term maintenance therapy for chronic lymphatic leukemia; Hodgkin's disease and some solid tumors also resolve.
Indications: Advanced ovarian adeno-Carcinoma, breast cancer, Hodgkin's disease, certain forms of non-Hodgkin lymphomas, chronic lymphocytic leukaemia. Waldenstram's macroglobinaemia.
Dosage: 4-10 mg (0.1-0.2 mg/kg) daily for 3-6 ks than 2 mg daily for maintenance
demonstrated resistant to the agent.
Special-Precautions: Altered fertility Haematological monitoring, lymphocytic infiltration. Carcinogenic potential. Paediatrics: Not recommended in infants. Pregnancy: Safety not established. Lactation: Safety not established. Elderly. No special precautions.
Side-effects: Hepatotoxicity, peripheral neuropathy, cystitis, seizures. Pulmonary firosis Fever.
Drug Interactions: Potentiation of other myelosuppressive agents. Phenyibutaone and warfarin potentiate the effect of chlonambucil.