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TACROLIMUS:
Indications: Orpphyaxi of organ rejection in patients receiving allogenic liver or kidney transplants.
Dosage: Kidney transplantation : 0.2mg/kg/day in adults as tow divided doses taken every 12 hrs. Liver trnaplantation : 0.10-0 15mgkkg/day in two divided doses taken every 12 hrs Maintenace dosage should be individualized so as to maintain whole blood concetracion between 5-200mg/ml.
Children: Generally need doses 1.5 to times greater than those in adults.