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ETHAMBUTOL : It is well absorbed through Gastro istinal Tract and has a long half life. Since it inhibits the growth of M. tuberculosis, use in conjugation with other anti tubercular is considered valuable.

Indication : Tuberculosis

Dosage : 15 mg/kg body wt daily as single dose Retreatment : 25 mg/kg body wt. as single dose for 60 days, then 15 mg/kg body wt. to be administered with other anti-tubercular medicines.

Contra-Indications : Hypersensitivity. Optic neuri­tis, Liver damage. Susceptibility to epilepsy.

Side effects : Dose related adverse effect of retro-bulbar neuritis of which the first signs are blurred vision and an inability to distinguish colours.

Special Precautions : Test visual functions before starting followed by periodic assessment of visual fields treatment. Impaired renal function.

Paediatrics: Not prescribed under age of 6 years.

Pregnancy: Safety not established.

Lactation: Use with caution.

Elderly: Reduced dose may be necessary.

Drug Interactions : Absorption reduced by alumin-ium hydroxide.

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