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Glucocorticoids are used topically for a large variety of dermatological
conditions. They benefit by virtue of their anti-infiammatory
immunosuppressive, vasoconstrictor & antiproliferative(for
scalling lesions) actions. The intensity of action depends n the
extent of absrption to the deeper layers, thus lipophilicity of
the compond determines potency to a great extent.
Indications: Eczema, psoriasis, otitis externa.
Lichen simplex & planus. Anal & vulval pruritus. Contact
dermatitis.
Contra Indications : Scabies, acne, perioral
dermatitis, furunculosis of skin. Chikenpox ^ herpes. Untreated
fungal or bacterial infections. Post vaccination skin erruptions.
Special Precautions : Sudden sithdrawal can
produce rebound exaceation of thecondition. Avoid eyes. Use on
face or children should be limited to 5 days.
Side-effects: Skin atrophy. Vellus hair growth.
Thinning of epidermis. Telangiectasia, striae. Delayed wound healing.
Fungal & bacterial infections. Systemically they can suppress
arenal pituitary. TOPICAL STEROIDS WITH ANTIMICROBIALS
In case where local inflammation is vary severe or there is evidence
of weeping lesions or there is superadded secondary bacterial
fungal infection. Antibiotics, antifungals keratolytic agents
are combined with steroidal preparation individually or in combination
as the need arises.
Indications : Impetigo, furunculosis, secondary
infected dermatoses, napkin rash, otitis externa, entertigonos
eruptions.