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CIPROFLOXACIN
It is an isotonic, sterile aqueous solution of ciprofloxacin Ictate, a potent fluoroquinolone derivative with bactericidal activity against a wide range of gram-positive & gram-negative pathogenic bacteria. It inhibitis bacterial DNA gyrase (Topoisomerase II), the enzyme responsible for introducing negative supercoils into the bacterial DNA. This leads to disruption of DNA structure and the death of bacteria.
Indications : EYE :Acute & subacute conjunctivitis, mucopurulent conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcer with or without hyopyon, bacterial keratitis and kerato conjunctivitis, chronic dacryocystitis, meibomanitis, preoperative prophylaxis in ocular surgery, treatment or post operative infections.
EAR: Otitis externa, acute otitis media, chronic suppurative otitis media & prophylaxis during otic surgeries such as mastoid surgery.
Dosage: Ocular infections: 1-2 drops into the affected eye(s) every 4 hrs.
Ear: 2-3 drops every 2-3 hrs.
Contra-indications: Hypersensitivity.
Special Precautions: Not for injection. If irritation persists or increases, discontinue. Don’t touch the dropper, since this may contaminate soln.
Side-effects: Mild transient smarting sensation & conjunctival congestion.