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Drugs recommanded are:

• Provera

INDICATIONS: Premenstrual syndrome, maintenance of pregnancy in case of threatened or habitual abortion, sterlity due to luteal deficiency. In menopause to reduce the risk of endometrial hyperplasia and carcinoma in post menopausal women receiving conjugated oestrogens, Puerperal depression.

CONTRAINDICATIONS: Hypersensitivity, undiagnosed vaginal bleeding, liver dysfunction, cerebral apoplexy, thrombophiebities, thromboembolic disorders.

SAFETY PROFILE: Migraine, asthma, epilepsy, renal dysfunction, driving or operating hazardous machinery should be avoided. Diabetic patients receiving oestrogen-progesterone combination therapy should be monitored.

ADVERSE EFFECTS: Drowsiness, giddiness, weight gain/loss/rash, diarrhea/menstrual irregulations.

DOSAGE: Maintenance of pregnancy in cases of habitual or threatened abortion : 200 400 mg per day in divided doses.

For premenstrual syndrome : 200-400 mg 1-2 times daily from the 12th to 14th day of the cycle until onset of menstruation.

For puerperal depression : 400 mg twice daily in divided doses.

Supplementation of the luteal phase in case of sterility due to luteal deficiency : 400 to 600 mg per day upto the 12th week of pregnancy.