Mexitil
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It is chemically & pharmacologically similar to lidocaine; a local anaesthetic, active antiarrhythmic by oral route.
INDICATIONS: Post infarction ventricular arrhythmias.
DOSAGE: Initially 400-600 mg followed after 2 hrs by maint. Dose of 200-350 mg 3-4 times daily.
CONTRA-INDICATIONS: Bradycardia, hypotension, conduction defects. Sinus node dysfunction.
SIDE-EFFECT: Dizziness, confusion, blurred vision, ataxia, tremor, vomiting.
DRUG INTERACTIONS: Ammonium chloride and phenytoin increases excretion rate of the drug. Sodium bicarbonate reduces excretion. Opiates delay absorption, useful combinations with Betablockers.