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It is the chirally pure form of amlodipine. It is twice as potent with lesser incidence of adverse effect like pheripheral edema as compared to racemic amlodipine. S(-) amlodipine has greater pharmacological activity and 1000 times more potent than R(+) isomer. Amlodipine inhibits the transmembrane influx of caclum into the vascular smooth muscles and cardiac smooth muscles.

INDICATIONS: Mild to moderate hypertension.

SIDE-EFFECTS: Amlodipine is associated with peripheral edema, headache, dizziness, flushing and abdominal and lower doses can be given and can also eliminate unwanted side effects.

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