Cpressin
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It is a synthetic polypeptide hormone, 8- L -lysine - vasopressin, having antidiuretic activity with no effects on electrolytes reabsorption, and has also activities of blood vessel contraction and blood clotting stimulation.
Indications: Pituitary diabetes insipidus; bleeding from oesophageal varices.
Dosage: I.V. , I.M. or subcutaneously.Adults:10 units (0.5ml). 20 units dissolved in 100 - 200ml of dextrose 5% soln is infused for more than 10 mins.
Contralndications: Vascular disease (especially disease of coronary arteries) unless extreme caution, chronic nephritis (until reasonable blood nitrogen concentrations attaid)
Side-effects: Pallor, nausea, belching, abdominal cramps, desire to defaccate, hypersensitivity reactions, constriction of coronary arteries (may cause angainal attacks and myocardial ischaemia)