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MIGLITOL: Miglito is a alph glcosidase inhibitor similar in action to acarbose.

Indications: In the management of type 2 diabetes mellitus alone or with a sulfonylurea.

Dosage: Usual initial doses are 25mg three times daily with meals, increased if necessary to max of 100mg three times daily

Contraindications: Hypersensitivity, renal clearance 25ml/min, GI motility disorder or the presence of inflammatory bowel disease, diabetic ketoacidosis, colonic ulceration or partial intestinal obstruction.

Drug interactions: Maglitol may significantly reduce the bioavailability of ranitidine and propranolo intestinal adsorbents (e.g. charcoal) and digestive enzyme preparations containing carbhydrate splitting enzymes (e.g. emylase, pancretain) may reduce the effect and should not be taken concomitantly.

Precautions: Hypoglycaemia.

Adverse reactions: Abdominal pain, diarrhea, flatulence, skin rash.

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