Alcefor
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CEFOPERAZONE SODIUM:It is a broad spectrum antibiotic, with high clinical efficacy and good toleration profile. Can be administered as immunotherapy or combination therapy in infections.
Indications: Respiratory tract infections. U.T.I Peritonitis. Cholecytitis cholangitis and other into abdominal infections: Septicemia: Meningitis; skin and soft tissue infection; infections of bone and anoints; Pelvic inflammatory disease, endometritis gonorrhea.
Dosage: 1gm or 2gm every 12 hrs. Severe infection: 8 gm per day. Gonococci arthritis: 500mgl. M single dose.
Contraindications: Hypersensitivity to cephalosporin’s and penicillin’s.
Special Precautions: Severe billiard obstruction or hepatic disease, Prothormbin time should be monitored, premature infants and neonates.
Pediatrics: Safety not established in age below 12 years.
Pregnancy: Use only, if clearly indicated.
Lactation: Use with caution; secreted in breast milk in low amounts.
Side effects: Allergic reactions, reversible neutropenia, Transient rise in SGOT. SGPT & alkaline phosphates. Eosinopilia, positive direct Como’s test anemia & reduced hematocrit.
Drug interactions: Enhances nephrotoxicity by amino glycosides, Disaffirm-like reaction with alcohol, Potentates anticoagulants.