Casodex
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Casodex (Bicalutamide)
US Brand: Casodex
Manufacturer: Other
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Indications : Prostate cancer, see notes above
Cautions: Hepatic impairment (Appendix 2), also consider periodic liver function tests;
Interactions : Appendix 1 (Bicalutamide).
Side-Effects: Dyspepsia, nausea, vomiting, diarrhea, abdominal pain, asthenia, depression, gynaecomastia, breast tenderness, decreated libido, hot flushesh, alopecia, hirsutism, prutius, dry skin, haematuria, cholestasis and jaundice (very rarely hepatic failure); rarely cardiovascular disorders (including angina, heart failure, conduction defects, arrhythmias and ECG changes); also reported, other gastro-intestional disorders, oedema, chest pain, dyspnoea, dry mouth headache, dizziness, insomnia, drowsiness, impotence, nocturia, rash, sweating, hyperglycaemina, weight changes; pelvic pain, anaemia, thrombocytopenia.
Dose: with orchidectomy or gonadoerlin therapy, 50 mg daily (in gonadorelin therapy, started 3 prostate cancer, 150 mg once daily.