Verenicline Changing product quantity in your shopping cart
When you have selected your item you can see your shopping cart items, quantity and total. You can change the quantity by entering the number of quantity you want. Then press 'Update' to change the quantity required.

How Champix works

Champix (Varenicline), a product of Pfizer, is an extensively researched drug and is the only one so far that is specifically designed to aid smoking cessation. A novel, non-nicotine, oral prescription medicine Varenicline, the active ingredient in Champix, has a novel dual mode of action. Unlike other smoking cessation solutions that work only on controlling the withdrawal symptoms, Champix reduces withdrawal symptoms and also the smoker’s sense of satisfaction derived from smoking.

Action 1:

Both nicotine (found in cigarettes and responsible for addiction to smoking) and Varenicline act on the nicotinic acetylcholine receptors (nAChRs) in the brain, which is associated with the addictive effects of nicotine. However unlike nicotine, Champix is a partial agonist of the receptors. So, when varenicline binds to these receptors it releases levels of dopamine that are required for normal functioning of the body. Hence, it reduces the craving to smoke and eases the withdrawal symptoms.

Action 2:

When the binding of nicotine to receptors is blocked by Varenicline, nicotine is unable to activate these receptors and cannot stimulate the release of dopamine - which produces the sense of satisfaction or pleasure and motivation in smokers. Hence it reduces both the craving to smoke and dependence on smoking to feel good.