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BCG Vaccine

BCG stands for Bacillus Calmette Gueri. BCG is used for the prevention of tuberculosis. It's a live freeze-dried vaccine derived from attenuated strain of mycobacterium bovis. BCG should strictly be injected via the intradermal route. The subcutaneous route should be avoided. After vaccination, generally no pain or fever is felt. BCG is always given on the left shoulder of a person. BCG vaccine is contraindicated in a disorder or disease in which natural immune response is altered. Therefore, strict supervision of an experienced physician is essential.

Two to Three weeks after the BCG vaccination, a papule develops at the site of vaccination. Its size increases upto 4-8 mm (diameter) in five weeks. Then it breaks into a shallow ulcer covered with a crust. But it heals spontaneously in six-twelve weeks. The BCG vaccination leaves a permanent round scar of Two-Ten mm in diameter

Technical detail

VACCINES AND IMMUNOGLOBULINS: These are the agents used for both active and passive

Once to infection following recovery from an infection or artificially through administration of vaccine. Passive immunisation is achieved by administration of antisera of antibodies in the form of antisera (of animal originlines (of human origin)

1. Vaccines : Immunisation vaccines are used for active immunisation against various disease. These are

BCG vaccines, Polio vaccines, Triple antigen, Diph­theria antitoxin, Measles vaccine, Meningitis vac­cine, Haemophilus b conjugate vaccine, Dual antigen, MMR, Influenza virus, Chicken pox vaccine, Hepatitis B vaccine Typhoid vaccine, Hepatitis A vaccine, Tetanus toxoid, Tetanus antitoxin, Cholera vaccine. Gas gangrene antitoxin, Pneumococcal vaccine, Rabies vaccine, Rubella vaccine, Anti snake venom injection.

ll.lmmunoglobulins : Tetanus immunoglobulin, Rabies, immunologibin, Human normal immunoglobin, Hepatitis B immune globin, Gamma globulin, Anti D immunoglobulin.

III. Immunostimulanis

Tinocordin

BCG VACCINE: it is a live bacterial vaccine. the vaccine is recommended in the prevention of primary tuberculosis, especially to prevent the most servious manifestations.

Dosage : 0.1ml intradermal from birth ot 2 weeks; on the upper part of the left arm.

Note : The vaccination causes a nodule at the site in about 4-6 weeks. This nodule gradually settles down but sometimes may break down and form a sore with some discharge, This sore needs to be cleaned with either soap and water or plain water.

Active Ingredients: Composition of 0.1ml of reconstituted vaccine. Lypholisate Attenuated live bacilli (derived from strain 1077) between 800000 and 3200000 units. Lypholisation excipients : Dextran, Glucose, Triton WR 1339, human albumin. Solvent : Water for injection upto 0.1ml. Injectable suspension is obtained by reconstituting the lypholisate with the solvent- vial of 10 doses to BCG