Engerix
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HEPATITES B SURFACE ANTIGEN
Each 1 ml dose contains 20 meg of hepatitis B surface antigen protein. Indications . Active immunization against hepatitis B virus infection.
Dosage and Administration : For intramuscular use only. In adults the injection should be given in the deltoid region, in neonates and in infants 'Engerix'-B should be administered in the anterolateral thigh. To be shaken well before use. A dose of 20 meg of antigen *-protein is recommended for adults and children 10 years of age and older. A dose of 10 meg of antigen neonates, infants and children below 10 years of age although a dose of 20 meg may also be used when a paedlatric dose is not available. Three doses should be given, 1st dose at elected date, 2nd dose 1 month later and 3rd dose - 6 months from the date of the first dose. For more rapid immunization the 3rd dose can be given two months after the initial dose with a booster at 12 months. It must not be given intravenously.
Contraindications : Hypersensitive to any component of the vaccine, severe febrile infections.
Special Precautions : Pregnant women. Adrenaline 1:1000 should be available for rare anaphylactic reaction.
Side effects : Mild transient soreness, erythema and induration at injection site. Occasionally low grade fever, malaise, fatigue, headache, nausea and dizziness.