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Letrozole is non steroidal antioestrogen drug.

INDICATIONS: Treatment of advanced breast cancer in post-menopausal women. Post menopausal women with localized harmone receptur positive breast cancer.

CONTRAINDICATIONS: Hypersensitivity, Pre menopausal women.

SAFETY PROFILE: Caution required in patient with severe renal impairment, blood counts should be monitored regularly.

ADVERSE EFFECTS: Nausea, vomiting, hot flushes pruitus, vaginal bleeding, dizzness diarrhea.

DRUG INTERACTIONS: None reported. DOSAGE: 2-5 mg OD.

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